Characterization of a common progenitor pool of the epicardium and myocardium

Forming the early heart The is first organ to form during development and critical for survival of embryo. precise molecular identities various cell types that make up these stages remain poorly defined. Tyser et al. used a combination transcriptomic, imaging, genetic lineage–labeling approaches profile identity locations cells involved in formation mouse embryonic heart. This approach allowed them identify earliest known progenitor epicardium, outermost layer heart, which an important source signals cardiac injury. Science , this issue p. eabb2986